1. Potential ability of hematoporphyrin to enhance an optical coherence tomographic image of gastric cancer in vivo in mice

    Abstract. An ideal diagnostic system for the tumor tissues should be able to detect and define the location of tumor tissues and the early development of malignant diseases. There is great need for enhancement of imaging ability to tumor tissues. Optical coherence tomography (OCT) is used in detection and location of varied tumor tissues. In order to improve the sensitivity and specificity of an OCT image, hematoporphyrin as a new type of contrast agent was used in this study. The orthotopic graft model of gastric cancer in nude mice was used. The image formations of the tumor tissues without and ...

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