1. Retinal Blood Flow Response to Hyperoxia Measured With En Face Doppler Optical Coherence Tomography

    Retinal Blood Flow Response to Hyperoxia Measured With En Face Doppler Optical Coherence Tomography

    Purpose : To use multiplane en face Doppler optical coherence tomography (OCT) to measure the change in total retinal blood flow (TRBF) in response to hyperoxia. Methods : One eye of each healthy human participant ( n = 8) was scanned with a commercial high-speed (70-kHz) spectral OCT system. Three repeated scans were captured at baseline and after 10 minutes of oxygen (hyperoxia) by open nasal mask. The procedure was performed twice on day 1 and once more on day 2. Blood flow of each vein was estimated using Doppler OCT at an optimized en face plane. The TRBF was summed from all veins ...

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