1. Corneal Epithelial Remodeling Induced by Small Incision Lenticule Extraction (SMILE)

    Corneal Epithelial Remodeling Induced by Small Incision Lenticule Extraction (SMILE)

    Purpose : To assess the reactive changes of the corneal epithelial thickness (ET) profile induced by small incision lenticule extraction (SMILE) for treatment of myopia. Methods : This prospective observational study included 46 eyes of 23 patients that were scheduled for myopic SMILE. High-resolution spectral-domain optical coherence tomography (SD-OCT) and a custom image segmentation algorithm were applied to measure corneal ET at multiple time points within the central 5-mm zone. Postoperative ET alterations were correlated with treatment parameters and refractive outcomes. Results : Mean age was 33 ± 6 years and mean spherical equivalent of surgical refractive correction was −4.78 ± 1.75 diopters ...

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