1. Validation of Dynamic optical coherence tomography for non-invasive, in vivo microcirculation imaging of the skin

    Validation of Dynamic optical coherence tomography for non-invasive, in vivo microcirculation imaging of the skin

    Objectives Dynamic optical coherence tomography (D-OCT) is anangiographic variation of OCT that non-invasively provides images of the in vivo microvasculature of the skin by combining conventional OCT images with flow data. The objective of this study was to investigate and report on the D-OCT technique for imaging of the vascular networks in skin as well as to validate the method by comparing the results against already accepted blood flow measuring tools. Methods 35 healthy subjects were recruited for the multicentre study, consisting of three experiments set up to examine the vascular blood perfusion during different induced physiologic changes in the ...

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