1. Outer retinal deformity detected by optical coherence tomography in eyes with foveal hypoplasia

    Outer retinal deformity detected by optical coherence tomography in eyes with foveal hypoplasia

    Purpose To investigate the relationship between vision and foveal maturity, especially in foveal hypoplasia exhibiting severe structural immaturity. Methods This retrospective observational case series included 42 eyes of 23 patients (mean age, 7.0 ± 5.0 years; 9 patients with foveal hypoplasia as an isolated entity and 14 patients with aniridia). A complete ophthalmic examination included measurement of best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography (SD-OCT). The sensory retina, ganglion cell complex (GCC), and outer retinal layers, including Henle’s fiber layer (HFL), were measured and analyzed. Results Using SD-OCT images, eyes were classified as having a differentiated ...

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