1. Cholesterol crystal as a new feature of coronary vulnerable plaques: An optical coherence tomography study

    Cholesterol crystal as a new feature of coronary vulnerable plaques: An optical coherence tomography study

    Background Previous pathohistological studies demonstrated that cholesterol crystals (CCs) are frequently observed in atherosclerotic plaques, and are usually present abundantly in vulnerable plaques. However, the role of CCs in plaque destabilization, as well as their origin and composition, is unknown. Optical coherence tomography (OCT) imaging system is a high-resolution imaging device, which allows the in vivo identification of CCs accumulating within atherosclerotic plaques. The aim of this study was to investigate the relationship between the presence of CCs, other plaque morphologies assessed by OCT, and patients’ clinical characteristics including acute coronary syndrome (ACS). Methods and results Preinterventional OCT images of ...

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