Outer Retinal Structural Alternation and Segmentation Errors in Optical Coherence Tomography Imaging in Patients with a History of Retinopathy of Prematurity

Purpose To evaluate retinal anatomy and segmentation errors from spectral domain optical coherence tomography (SD-OCT) imaging (MM5 protocol of RTVue-100; Optovue, Inc., Fremont, CA) in school-aged children. Design A prospective cohort study in a referral medical center. Methods 133 eyes of 133 patients were enrolled. Patients were grouped as those who were treated for retinopathy of prematurity (ROP) (ROP-Tx-group); those with spontaneously-regressed ROP (ROP-non-Tx-group); other premature patients (premature group); and full-term age-matched children (full-term group). Anatomy and segmentation errors of retina were evaluated by SD-OCT. Results The mean age at assessment was 9.5 years (range 4–16 years). The ...
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