1. The Mystery of Spotty Calcification Can We Solve It by Optical Coherence Tomography?

    The Mystery of Spotty Calcification Can We Solve It by Optical Coherence Tomography?

    Spotty calcification has recently been introduced as a marker of plaque vulnerability in patients presenting with acute coronary syndrome undergoing invasive and noninvasive coronary imaging, 1 and it has been suggested to be of predictive value for percent atheroma volume with greater progression. 2 Several pathological and clinical studies applying computed tomography (CT) and intravascular ultrasound (IVUS) demonstrated that spotty calcification is more frequently observed in lesions with plaque rupture compared with stable plaque. 3 , 4 Recently, optical coherence tomography (OCT) has emerged as the premier intracoronary imaging technology with a higher resolution (10–20 μm) than IVUS (100–200 ...

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