1. Spectral-Domain Optical Coherence Tomography Imaging in 67,321 Adults

    Spectral-Domain Optical Coherence Tomography Imaging in 67,321 Adults

    Purpose To derive macular thickness measures and their associations by performing rapid, automated segmentation of spectral-domain optical coherence tomography (SD OCT) images collected and stored as part of the UK Biobank (UKBB) study. Design Large, multisite cohort study in the United Kingdom. Analysis of cross-sectional data. Participants Adults from the United Kingdom aged 40 to 69 years. Methods Participants had nonmydriatic SD OCT (Topcon 3D OCT-1000 Mark II; Topcon GB, Newberry, Berkshire, UK) performed as part of the ocular assessment module. Rapid, remote, automated segmentation of the images was performed using custom optical coherence tomography (OCT) image analysis software (Topcon ...

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