1. Reconstruction of 3D surface maps from anterior segment optical coherence tomography images using graph theory and genetic algorithms

    Reconstruction of 3D surface maps from anterior segment optical coherence tomography images using graph theory and genetic algorithms

    Automatic segmentation of anterior segment optical coherence tomography images provides an important tool to aid management of ocular diseases. Previous studies have mainly focused on 2D segmentation of these images. A novel technique capable of producing 3D maps of the anterior segment is presented here. This method uses graph theory and dynamic programming with shape constraint to segment the anterior and posterior surfaces in individual 2D images. Genetic algorithms are then used to align 2D images to produce a full 3D representation of the anterior segment. In order to validate the results of the 2D segmentation comparison is made to ...

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