1. Assessing the influence of biofilm surface roughness on mass transfer by combining optical coherence tomography and two-dimensional modeling

    Assessing the influence of biofilm surface roughness on mass transfer by combining optical coherence tomography and two-dimensional modeling

    Imaging and modeling are two major approaches in biofilm research to understand the physical and biochemical processes involved in biofilm development. However, they are often used separately. In this study we combined these two approaches to investigate substrate mass transfer and mass flux. Cross-sectional biofilm images were acquired by means of optical coherence tomography (OCT) for biofilms grown on carriers. A 2D biofilm model was developed incorporating OCT images as well as a simplified biofilm geometry serving as structural templates. The model incorporated fluid flow, substrate transfer and biochemical conversion of substrates and simulated the hydrodynamics surrounding the biofilm structure ...

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