1. Optical coherence tomography imaging of coronary atherosclerosis is affected by intraobserver and interobserver variability

    Optical coherence tomography imaging of coronary atherosclerosis is affected by intraobserver and interobserver variability

    Aims: Optical coherence tomography (OCT) has emerged as a novel imaging modality that allows plaque classification through identification of features including lipid, calcification and fibrous cap. However, subtle changes in light attenuation as the optical beam traverses the plaque in vivo are challenging to interpret and data on strength of observer agreement are minimal. Thus, we sought to assess both the intra and interobserver variability for plaque composition/classification using OCT. Methods: OCT imaging was performed in 50 patients prior to percutaneous coronary intervention. Analysis was performed offline by two independent, experienced OCT operators. Target lesion luminal dimensions and plaque ...

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