1. Evaluation of Coronary Arterial Calcification - Ex-vivo Assessment by Optical Frequency Domain Imaging

    Evaluation of Coronary Arterial Calcification - Ex-vivo Assessment by Optical Frequency Domain Imaging

    Aims The purpose of this study was to determine the diagnostic ability of optical frequency domain imaging (OFDI) to carry out quantitative and qualitative evaluation of coronary calcification in comparing with ex vivo human autopsy heart specimens. Methods Analysis was carried out in 25 coronary artery specimen obtained from 16 cadavers that were imaged ex-vivo imaging by OFDI and intravascular ultrasound (IVUS). Of 235 cross-sections obtained for histologic evaluation, 149 were classified as showing calcified plaques, and in this group a comparison between histology versus co-registered images by OFDI and IVUS was performed. Results Maximum thickness of calcification measured by ...

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