1. Functional and high-resolution retinal imaging monitoring photoreceptor damage in acute macular neuroretinopathy

    Functional and high-resolution retinal imaging monitoring photoreceptor damage in acute macular neuroretinopathy

    Background To report functional and high-resolution retinal imaging abnormalities, including adaptive optics (AO) throughout the course of acute macular neuroretinopathy (AMNR). Methods Two female patients (four eyes) with a diagnosis of AMNR were observed at the Clinical Investigation Center, CHNO des Quinze-Vingts, Paris, France. The patients underwent detailed ophthalmic examination including best-corrected visual acuity, slit-lamp examination, kinetic and static perimetry, full-field and multifocal electroretinogram, infrared reflectance, autofluorescence imaging and spectral-domain optical coherence tomography (SD-OCT) and AO fundus imaging at presentation and during follow-up. Results Both cases showed concomitant loss of integrity of the outer retinal structures on SD-OCT, and marked ...

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