1. Noninvasive Vascular Imaging of Polypoidal Choroidal Vasculopathy by Doppler Optical Coherence Tomography

    Noninvasive Vascular Imaging of Polypoidal Choroidal Vasculopathy by Doppler Optical Coherence Tomography

    Purpose. To noninvasively investigate the vascular architecture of polypoidal lesions in polypoidal choroidal vasculopathy (PCV) using Doppler optical coherence tomography (OCT), and to evaluate the clinical usefulness of Doppler OCT for the assessment of therapeutic effects in PCV. Methods. Fifteen eyes of 15 patients with treatment-naïve PCV were prospectively studied. Vascular imaging was obtained using 1060-nm swept-source Doppler OCT, and compared with indocyanine green angiography (ICGA) images. The therapeutic effect of three consecutive intravitreal aflibercept injections was evaluated with ICGA and Doppler OCT. Results. In Doppler OCT images, polypoidal lesions were clearly detected at the corresponding locations of lesions ...

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