1. PEGylated Aucore–Agshell Nanorods as Optical Coherence Tomography Signal Nanoamplifiers

    PEGylated Aucore–Agshell Nanorods as Optical Coherence Tomography Signal Nanoamplifiers

    Optimizing contrast enhancement in optical coherence tomography (OCT) is essential for producing specific image signals and realizing its potential use in various biomedical imaging fields besides ophthalmology and cardiology. Using nanoparticles as selective signal nanoamplifiers will be helpful to highlight the lesion sites and identify cancerous changes that are difficult to diagnose currently. In this study, a quantitatively detailed analysis on the improvement of contrast enhancement and penetration depth of Au core –Ag shell nanorods (Au@Ag NRs) as OCT contrast agent was performed. The average A-scan data of the tissue was extracted and investigated. The signal to noise ratio ...

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