Intra- and Inter-Frame Differential Doppler Optical Coherence Tomography

Spectrometer based optical coherence tomography suffers from fringe washout for fast flow, a drawback for flow visualization, which is of interest for both lable-free optical angiography and flow quantification. We presented a method, which can be used to contrast very fast flows, while maintaining relatively low A-scan rates. It is based on introducing a phase shift of during acquisition such that the interference fringes associated to moving sample structures are recovered depending on the axial velocity. This enables the use of slower line scan cameras for measuring the fast blood flows within the large vessels in the region of the ...
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