Adaptive Optics Fundus Camera to Examine Localized Changes in the Photoreceptor Layer of the Fovea

Entities Mentioned

• Osaka University Medical School

1. Purpose: To examine highly localized photoreceptor disruptions in the fovea by a high-resolution adaptive optics (AO) fundus camera combined with Fourier-domain optical coherence tomography (FD OCT).Design: Observational case series.Participants: Three eyes of 3 patients who showed dark foveal spots by slit-lamp biomicroscopy.Methods: Three patients who reported metamorphopsia but showed no changes in the retina in conventional fundus photographs were examined. High-resolution retinal images were obtained with the AO fundus camera and by FD OCT. The images were compared with the findings obtained by standard clinical tests, including Amsler charts and fluorescein angiography (FA).Main Outcome Measures: Quantitative measurements of the area ... (Read Full Article)

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