1. Macular Thickness Profiles of Intra-retinal Layers in Myopia Evaluated by Ultra-High Resolution Optical Coherence Tomography

    Macular Thickness Profiles of Intra-retinal Layers in Myopia Evaluated by Ultra-High Resolution Optical Coherence Tomography

    Purpose To investigate the thickness and variation profiles of eight intra-retinal layers in myopia. Design Prospective cross-sectional study. Methods Young subjects with spherical equivalents ranging from +0.50 to -10.25 diopters and good corrected vision were divided into emmetropic (n=20), low myopic (n=50), and high myopic (n=30) groups. Retinal images centered on the fovea along the horizontal and vertical meridians were obtained by ultra-high resolution optical coherence tomography (OCT). Macular images were segmented into eight intra-retinal layers by an automatic segmentation algorithm to yield thickness profiles within a 6-mm diameter circle divided into central, pericentral, and ...

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