1. Approach to quantify two-dimensional strain of chick embryonic heart in early stage based on spectral domain optical coherence tomography

    Approach to quantify two-dimensional strain of chick embryonic heart in early stage based on spectral domain optical coherence tomography

    The heart undergoes remarkable changes during embryonic development due to genetic programming and epigenetic influences, in which mechanical loads is a key factor. As embryonic research development, an important goal is to develop mathematical models that describe the influence of mechanics on embryonic heart development. However, basic parameters for the modeling are difficult to acquire since the embryonic heart is tiny and beating fast in the early stages. Optical coherence tomography (OCT) technique provides depth-resolved image with high resolution and high acquisition speed in a noninvasive manner. In this paper, we performed 4D[(x,y,z) + t] scan on the ...

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