1. Evaluation of a Method for Estimating Retinal Ganglion Cell Counts Using Visual Fields and Optical Coherence Tomography

    Evaluation of a Method for Estimating Retinal Ganglion Cell Counts Using Visual Fields and Optical Coherence Tomography

    Purpose : To evaluate the accuracy and generalizability of a published model that derives estimates of retinal ganglion cell (RGC) counts and relates structural and functional changes due to glaucoma. Methods : Both the Harwerth et al. non−linear model (H−NLM) and the Hood and Kardon linear model (HK−LM) were applied to an independent dataset of frequency−domain optical coherence tomography and visual fields, consisting of 48 eyes of 48 healthy controls, 100 eyes of 77 glaucoma patients and suspects, and 18 eyes of 14 non−arteritic anterior ischemic optic neuropathy (ION) patients with severe vision loss. Using the coefficient ...

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