1. Lamina Cribrosa Visibility using Optical Coherence Tomography: Comparison of Devices and Effects of Image Enhancement Techniques

    Lamina Cribrosa Visibility using Optical Coherence Tomography: Comparison of Devices and Effects of Image Enhancement Techniques

    Purpose: To compare the visibility of the lamina cribrosa (LC) in optic disc images acquired from 60 glaucoma and 60 control subjects using three optical coherence tomography (OCT) devices, with and without enhanced depth imaging (EDI) and adaptive compensation (AC). Methods: A horizontal B-scan was acquired through the centre of the disc using two spectral-domain (Spectralis and Cirrus; with and without EDI) and a swept-source (DRI) OCT. AC was applied post-acquisition to improve image quality. To assess LC visibility, four masked observers graded the 1,200 images in a randomised sequence. The anterior LC was graded from 0 to 4 ...

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