1. Development and evaluation of a device for simultaneous uniaxial compression and optical imaging of cartilage samples in vitro

    Development and evaluation of a device for simultaneous uniaxial compression and optical imaging of cartilage samples in vitro

    In this paper, we present a system that allows imaging of cartilage tissue via optical coherence tomography (OCT) during controlled uniaxial unconfined compression of cylindrical osteochondral cores in vitro . We describe the system design and conduct a static and dynamic performance analysis. While reference measurements yield a full scale maximum deviation of 0.14% in displacement, force can be measured with a full scale standard deviation of 1.4%. The dynamic performance evaluation indicates a high accuracy in force controlled mode up to 25 Hz, but it also reveals a strong effect of variance of sample mechanical properties on the ...

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