1. Comparison of Circulating Dendritic Cells and Monocyte Subsets at Different Stages of Atherosclerosis: insights from optical coherence tomography

    Comparison of Circulating Dendritic Cells and Monocyte Subsets at Different Stages of Atherosclerosis: insights from optical coherence tomography

    Objectives Proinflammatory dendritic cells (DC) and monocytes are critically involved in the proceeding and destabilization of atherosclerosis. Recent studies have reported potential associations of specific patterns of circulating DCs and monocytes with the incidence of coronary artery disease (CAD) and ST-elevation myocardial infarction (STEMI); however, further information of DC and monocyte subsets on plaque morphology and vulnerability is uncertain and required. Methods Forty-seven CAD patients with borderline lesions (stenosis 50%-70%) by coronary angiography (CAG) were enrolled, while 31 subjects free of luminal diameter narrowing ≥ 50% served as controls. Likewise, 35 patients with STEMI were enrolled and confirmed with the ...

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