Macular Thickness Measurements in Normal Eyes Using Spectral Domain Optical Coherence Tomography

Entities Mentioned

• Carl Zeiss Meditec
• Zeiss Stratus OCT
• University of Southern California
• Giovanni Gregori
• Carmen A. Puliafito
• Robert W. Knighton
• University of Miami
• Zeiss Cirrus HD-OCT

1. BACKGROUND AND OBJECTIVE Knowledge of the macular thickness in a normal population is important for the evaluation of pathological macular change. The purpose of this study was to define and measure macular thickness in normal eyes using spectral domain optical coherence tomography (OCT). PATIENTS AND METHODS Fifty eyes from 50 normal subjects (29 men and 21 women, aged 22 to 68 years) were scanned with a prototype Cirrus HD-OCT system (5 µm axial resolution) (Carl Zeiss Meditec, Inc.). The proprietary Cirrus segmentation algorithm was used to produce retinal thickness maps, which were then averaged over 9 regions ... (Read Full Article)

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