Spectral Domain Optical Coherence Tomographic Imaging of Geographic Atrophy

Entities Mentioned

• Carl Zeiss Meditec
• University of Southern California
• Giovanni Gregori
• Philip J. Rosenfeld
• Carmen A. Puliafito
• Robert W. Knighton
• University of Miami

1. BACKGROUND AND OBJECTIVE To compare images of geographic atrophy (GA) obtained using spectral domain optical coherence tomography (SD-OCT) with images obtained using auto fluorescence (FAF). PATIENTS AND METHODS Five eyes from patients with dry AMD were imaged using SD-OCT and FAF, and the size and shape of the GA were compared. RESULTS GA appears bright on SD-OCT compared with the surrounding areas with an intact retinal pigment epithelium because of increased reflectivity from the underlying choroid. SD-OCT and FAF both identified GA reproducibly, and measurement of the area of GA is comparable between the two methods with a mean difference ... (Read Full Article)

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