1. A Novel OCT technique to Measure in vivo the Corneal Adhesiveness for Sodium Carboxymethylcellulose in Humans and its validity in the Diagnosis of Dry Eye

    A Novel OCT technique to Measure in vivo the Corneal Adhesiveness for Sodium Carboxymethylcellulose in Humans and its validity in the Diagnosis of Dry Eye

    Purpose: The purpose of this work was to gather preliminary data on tear film stability and the adhesive properties of the corneal surface in dry eye patients and control-group subjects, using a new, minimally invasive OCT imaging method. Methods: Eighty-five human subjects were screened for dry eye and classified in two groups, as dry eye or normal patients. Sodium carboxymethylcellulose (NaCMC) adhesiveness over the central cornea was measured using Fourier Domain anterior segment optical coherence tomography (OCT). The corneal adhesiveness for NaCMC was compared between the two groups, correlated with classical tests, and analyzed for diagnostic validity and repeatability. Results ...

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