Dynamic variation of hemodynamic shear stress on the walls of developing chick hearts: computational models of the heart outflow tract
Abstract Heart morphogenesis and growth are influenced by hemodynamic forces (wall shear stress and blood pressure) acting on the walls
of the heart. Mechanisms by which hemodynamic forces affect heart development are not well understood, in part because of
difficulties involved in measuring these forces in vivo. In this paper, we show how wall shear stress in the heart outflow
tract (OFT) of chick embryos at an early developmental stage (HH18) are affected by changes in the geometry and motion of
the OFT wall. In particular, we were interested in the effects of cardiac cushions, which are protrusions of the ...
Read Full Article
Login to comment.