1. New Insights on Plaque Erosion and Calcified Nodules “Seeing Is Believing”

    New Insights on Plaque Erosion and Calcified Nodules “Seeing Is Believing”

    Plaque erosion (PE) and calcified nodules (CN) have been classically described in pathological studies as causes of acute coronary syndromes (ACS) ( 1 ). However, until very recently, the diagnosis of these entities in the clinical setting has remained largely elusive ( 1 ). In this regard, the study of Jia et al. 2 , using optical coherence tomography (OCT) for the diagnosis of PE and CN, is of major clinical interest and raises several important issues. First, the investigators considered that OCT might provide a “definitive” diagnosis of PE when fibrous cap disruption is excluded and a thrombus overlying an “intact” plaque is visualized ...

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