1. Paracentral acute middle maculopathy spectral-domain optical coherence tomography feature of deep capillary ischemia

    Paracentral acute middle maculopathy spectral-domain optical coherence tomography feature of deep capillary ischemia

    Purpose of Review: To describe the novel spectral-domain optical coherence tomography (SD-OCT) finding of paracentral acute middle maculopathy (PAMM) that can be associated with acute macular neuroretinopathy (AMN) or retinal vasculopathy, and that may indicate an underlying pathogenesis related to ischemia of the retinal deep capillary plexus (DCP). Recent Findings: With the advent of high-definition SD-OCT imaging, we are now able to detect deep capillary ischemia. Although cotton wool spots are caused by ischemia of the superficial capillary plexus, PAMM is caused by ischemia of the DCP, and appears as hyper-reflective, band-like lesions in the middle retina, extending from the ...

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