1. Optical Coherence Tomography Features of POEMS Syndrome and Castleman Disease-associated Papillopathy

    Optical Coherence Tomography Features of POEMS Syndrome and Castleman Disease-associated Papillopathy

    Purpose : To report ocular symptoms and optical coherence tomography (OCT) features of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome. Methods : Case report of two Caucasian patients with POEMS, one of whom also had multicentric Castleman disease. Results : Both patients presented with edema on both optic disks, bilateral macular edema was seen in case 1, and peripapillary choroidal neovascularization was seen on the right side in case 2. OCT confirmed papilledema involving all retinal layers, with additional bilateral peripapillary serous retinal detachment involving the macula in both cases, and peripapillary CNV in case 2. Changes in retinal nerve ...

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