1. Comparison of Dynamic Changes in Anterior Ocular Structures Examined with Anterior Segment Optical Coherence Tomography in a Cohort of Various Origins

    Comparison of Dynamic Changes in Anterior Ocular Structures Examined with Anterior Segment Optical Coherence Tomography in a Cohort of Various Origins

    Purpose: To identify risk factors for angle closure from iris and angle anterior segment optical coherence tomography (ASOCT) measurements and to determine if these differ by geographic origin. Methods: ASOCT images from 267 clinic-based persons were compared between bright and dark conditions. An automated program quantified angle and iris parameters. Results: Iris area in bright light was larger with increasing age (univariate regression, p=0.0005), and largest in European and African-derived and smallest in Korean and Chinese eyes (multivariable regression, p=0.0001). Iris area was significantly larger in AC groups compared to normal and open angle glaucoma groups ...

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