1. The design, development and application of a dual-beam spectral-domain optical coherence tomography system for the non-invasive assessment of vascular dynamics by statistical means (Thesis)

    The design, development and application of a dual-beam spectral-domain optical coherence tomography system for the non-invasive assessment of vascular dynamics by statistical means (Thesis)

    This assertion underscores the importance of haematological dynamic assessment, which can benefit greatly from non-invasive high-resolution imaging of blood flow especially at the microvascular level. This importance is further highlighted in oncological applications with recent emphasis on tumour vasculature, angiogenic processes and developments of anti-angiogenic therapies. Optical coherence tomography (OCT) has established itself a firm foothold in the realm of non-invasive optical medical diagnostic imaging, enabling in vivo cross-sectional tomographic visualisation of the internal microstructure of biological systems, and is now considered an optical analogue to CT or MRI, but with microscopic resolution. The original concept of OCT was to ...

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