Feature Of The Week 1/19/14: Feature Of The Week: Irish Researchers Investigate Correlation of FFR and OCT Measured Parameters for Identifying Coronary Stenosis
The usefulness of fractional flow reserve (FFR) in the functional evaluation of intermediate coronary stenosis is well established. Similarly, intracoronary optical coherence tomography (OCT) continues to be a promising imaging technique for the assessment of coronary artery disease. The frequency domain OCT (FD-OCT) provides faster image acquisition speeds, higher frame rates and greater scan depths as compared to time domain OCT while preserving the image quality. The main aim of this study was to determine the correlation between FFR and frequency domain OCT (FD-OCT) measured anatomical parameters that include minimal lumen area (MLA), minimal lumen diameter (MLD) and percent lumen area stenosis (%AS). The diagnostic efficiency of FD-OCT in identifying severe coronary stenosis is also included in this study. 41 coronary stenoses in 30 patients were assessed consecutively by quantitative coronary angiography (QCA), FFR and FD-OCT. The FFR values and FD-OCT measured anatomical parameters MLA, MLD and %AS were found to be significantly correlated. In the overall group, the FD-OCT measured MLA and MLD have shown moderate diagnostic efficiency in the evaluation of significant coronary stenosis. FD-OCT measured MLA has high diagnostic efficiency in identifying severe coronary stenosis in vessels having reference diameter < 3 mm.
For more information see recent Article. Courtesy Haroon Zafar from National University of Ireland, Galway.