1. Handheld Optical Coherence Tomography During Sedation in Young Children With Optic Pathway Gliomas

    Handheld Optical Coherence Tomography During Sedation in Young Children With Optic Pathway Gliomas

    Importance Monitoring young children with optic pathway gliomas (OPGs) for visual deterioration can be difficult owing to age-related noncompliance. Optical coherence tomography (OCT) measures of retinal nerve fiber layer (RNFL) thickness have been proposed as a surrogate marker of vision but this technique is also limited by patient cooperation. Objective To determine whether measures of circumpapillary RNFL thickness, acquired with handheld OCT (HH-OCT) during sedation, can differentiate between young children with and without vision loss from OPGs. Design, Setting, and Participants This cross-sectional analysis of a prospective observational study was conducted at a tertiary-care children’s hospital. Children with an ...

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