1. Special Section Guest Editorial: Optical Elastography and Measurement of Tissue Biomechanics

    Special Section Guest Editorial: Optical Elastography and Measurement of Tissue Biomechanics

    Since the days of Hippocrates, it has been recognized that tissue mechanical properties can play a key role in the diagnosis and understanding of many diseases. For example, in cancer, the stromal response associated with tumor progression often results in stiffening of tissue surrounding tumor cells. In cardiovascular disease, atherosclerotic plaque mechanics are linked to plaque rupture. Elastography—the use of medical imaging to map the mechanical properties of tissue—has been developed extensively over the past 25 years, based mainly on ultrasound and magnetic resonance imaging. These methods continue to develop, are available commercially, and are finding ever-growing application ...

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