1. Macular spectral domain optical coherence tomography findings in Tanzanian endemic optic neuropathy

    Macular spectral domain optical coherence tomography findings in Tanzanian endemic optic neuropathy

    Bilateral optic neuropathy in Dar es Salaam is now considered endemic and is estimated to affect 0.3–2.4% of young adults. The condition is characterized by a subacute bilateral loss of central vision of unknown aetiology. Findings of spectral domain optical coherence tomography have not previously been reported for these patients. All patients diagnosed with endemic optic neuropathy over a 2-year period at the Muhimbili National Hospital underwent spectral domain optical coherence tomography macular imaging. Scans were graded qualitatively for severity of retinal nerve fibre layer loss as well as the presence of microcystic macular changes, which have ...

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