1. Effect of Contact Lens on Optical Coherence Tomography Imaging of Rodent Retina

    Effect of Contact Lens on Optical Coherence Tomography Imaging of Rodent Retina

    Visibility of optical coherence tomography (OCT) images can be severely degraded by speckle noise. A computationally efficient despeckling approach that strongly reduces the speckle noise is reported. It is based on discrete wavelet transform (DWT), but eliminates the conventional process of threshold estimation. By decomposing an image into different levels, a set of sub-band images are generated, where speckle noise is additive. These sub-band images can be compounded to suppress the additive speckle noise, as DWT coefficients resulting from speckle noise tend to be approximately decorrelated. The final despeckled image is reconstructed by taking the inverse wavelet transform of the ...

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