1. Cluster analyses of grid-pattern display in macular parameters using optical coherence tomography for glaucoma diagnosis

    Cluster analyses of grid-pattern display in macular parameters using optical coherence tomography for glaucoma diagnosis

    Purpose: Using spectral-domain optical coherence tomography (SD-OCT), we assessed the ability of cluster analyses based on the grid-pattern of macular parameters to detect glaucoma. Methods: Seventy-five normal eyes, 64 early glaucomatous eyes (EG) and 40 preperimetric glaucomatous eyes (PPG) were enrolled. Each participant was imaged using 3D OCT to examine the macular retinal nerve fiber layer (mRNFL) and the thickness of the ganglion cell layer together with the inner plexiform layer (GCL/IPL). Diagnostic criteria based on the clustering of abnormal grids from the mRNFL and GCL/IPL measurements were applied. The sensitivity and specificity of glaucoma detection were compared ...

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