1. Photocoagulation in rabbits: Optical coherence tomographic lesion classification, wound healing reaction, and retinal temperatures

    Photocoagulation in rabbits: Optical coherence tomographic lesion classification, wound healing reaction, and retinal temperatures

    Background and Objective The rabbit is the most common animal model to study retinal photocoagulation lesions. We present a classification of retinal lesions from rabbits, that is based on optical coherence tomographic (OCT) findings, temperature data, and OCT-follow-up data over 3 months. Materials and Methods Four hundred eighty-six photocoagulation lesions (modified Zeiss Visulas® 532 nm CW laser, lesion diameter 133 µm, exposure duration 200 milliseconds or variable, power variable) were analyzed from six eyes of three chinchilla gray rabbits. During the irradiation of each lesion, we used an optoacoustics-based method to measure the retinal temperature profile. Two hours, 1 week ...

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