1. A high speed three-dimensional spectral domain optical coherence tomography with <2 μm axial resolution using wide bandwidth femtosecond mode-locked laser

    A high speed three-dimensional spectral domain optical coherence tomography with <2 μm axial resolution using wide bandwidth femtosecond mode-locked laser

    We have developed an ultra-high-resolution optical coherence tomography (OCT) equipment, using a 200 nm bandwidth spectrometer and a mode-locked femtosecond laser. We have characterized this OCT, obtaining high spatial resolution in the axial direction of less than 2  μ m in air via single scanning, within only 20 ms. This corresponds to an ultra-high resolution of less than 1.3  μ m for measurements at the fundus retina. High resolution and high speed imaging enables us to selectively obtain a clear three dimensional (3D) lamina cribrosa itself from a 3D optic disc (OD) image in vivo .

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