1. Simultaneous determination of the tissue light scattering coefficient and Brownian diffusion coefficient using optical coherence tomography

    Simultaneous determination of the tissue light scattering coefficient and Brownian diffusion coefficient using optical coherence tomography

    Diseased tissue has different optical properties and dynamic behaviors from normal tissue, and this can be exploited for diagnostics and therapeutics. We present a model for simultaneously estimating the optical scattering coefficient and Brownian diffusion coefficient of superficial biological tissue. This theoretical model predicts that the U-quadratic distribution approximates the Lorentzian power spectrum due to the Brownian motion, when the frequency width of integration is much less than the power spectrum linewidth. Furthermore, it shows that the logarithmic intensity of all calculated wavelet frequencies is linearly dependent on the scattering coefficient and the standard deviation of the Doppler frequency shift ...

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