1. Combining light and sound for retinal imaging

    Combining light and sound for retinal imaging

    Photoacoustic ophthalmoscopy provides exceptional contrast when visualizing the retina, assisting in the early diagnosis of some eye diseases. The diagnosis, treatment, and prognosis of eye diseases have greatly benefited from innovation in modern ophthalmic imaging technologies. Photoacoustic ophthalmoscopy (PAOM) is a 3D imaging method that allows non-invasive visualization of the back of the eye through angiography (where an x-ray-based technique is used to create an image). But unlike an angiogram, the image is made using no exogenous contrast agents. 1–3 PAOM instead uses the endogenous light-absorption contrast from hemoglobin and melanin to generate images of the retina's vascular ...

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