1. Comparison of Dresen Area Detected by Spectral Domain Optical Coherence Tomography and Color Fundus Imaging

    Comparison of Dresen Area Detected by Spectral Domain Optical Coherence Tomography and Color Fundus Imaging

    Purpose: To compare the measurements of drusen area from manual segmentation of color fundus photographs with those generated by an automated algorithm designed to detect elevations of the retinal pigment epithelium (RPE) on spectral domain optical coherence tomography (SDOCT) images. Methods: Fifty eyes with drusen secondary to non-exudative age-related macular degeneration (AMD) were enrolled. All eyes were imaged with the Cirrus HD-OCT instrument (Carl Zeiss Meditec, Dublin, CA) using a 200x200 A-scan raster pattern covering a 6mm X 6mm area centered on the fovea. Digital color fundus images were taken on the same day. Drusen were traced manually on the ...

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