1. Multimodal Evaluation of Foveal Sparing in Patients With Geographicatrophy Due to Age-Related Macular Degeneration

    Multimodal Evaluation of Foveal Sparing in Patients With Geographicatrophy Due to Age-Related Macular Degeneration

    Purpose: To compare the ability of spectral domain optical coherence tomography (SD-OCT), blue light fundus autofluorescence (FAF), and near-infrared fundus autofluorescence (NIR-FAF) to evaluate foveal involvement in geographic atrophy as a result of age-related macular degeneration. Methods: All consecutive patients with geographic atrophy underwent FAF (excitation [lambda] = 488 nm; emission [lambda] > 500 nm), NIR-FAF (excitation [lambda] = 787 nm; emission [lambda] > 800 nm), and simultaneous SD-OCT scanning (Spectralis HRA + OCT; Heidelberg Engineering). Two readers independently graded foveal involvement on FAF, NIR-FAF, and SD-OCT and measured the width of foveal sparing. In eyes with an intergrader agreement of foveal sparing by at ...

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