1. Diagnostic Capability of Lamina Cribrosa Thickness by Enhanced Depth Imaging and Factors Affecting Thickness in Patients with Glaucoma

    Diagnostic Capability of Lamina Cribrosa Thickness by Enhanced Depth Imaging and Factors Affecting Thickness in Patients with Glaucoma

    Objective To determine the diagnostic ability of laminar thickness obtained using enhanced depth imaging (EDI) of the Heidelberg Spectralis optical coherence tomography (OCT) system (Heidelberg Engineering, Heidelberg, Germany) and the factors related to laminar thickness in patients with glaucoma. Design Evaluation of a diagnostic test. Participants A total of 144 patients with glaucoma (68 with primary open-angle glaucoma [POAG], 76 with normal-tension glaucoma [NTG]), and 65 healthy controls. Methods All patients underwent retinal nerve fiber layer (RNFL) thickness and optic nerve head (ONH) scanning with the Spectralis OCT system. Mean laminar thickness was defined at the center of the mid-superior ...

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