1. Semiautomated Segmentation of the Choroid in Spectral-domain Optical Coherence Tomography Volume Scans

    Semiautomated Segmentation of the Choroid in Spectral-domain Optical Coherence Tomography Volume Scans

    Purpose: Changes in the choroid, in particular its thickness, are believed to be of importance in the pathophysiology of a number of retinal diseases. The purpose of this study is to adapt the graph search algorithm to semi-automatically identify the choroidal layer in spectral-domain optical coherence tomography (SD-OCT) volume scans and compare its performance to manual delineation. Methods: A graph-based multi-stage segmentation approach was used to identify the choroid, defined as the layer between the outer border of the retinal pigment epithelium (RPE) band and the choroid-sclera junction. Thirty randomly chosen macular SD-OCT (Heidelberg Spectralis) volumes were obtained from 20 ...

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