1. Keratoconus diagnosis using anterior segment polarization-sensitive optical coherence tomography

    Keratoconus diagnosis using anterior segment polarization-sensitive optical coherence tomography

    Purpose: To investigate the tissue properties of keratoconic corneas and normal control in vivo by using polarization-sensitive optical coherence tomography (PS-OCT) and evaluate early keratoconus by the area under the receiver-operating curve and Mahalanobis distances analysis. Methods: Thirty one eyes of 20 patients with keratoconus, seven eyes of four patients with keratoconus suspect, and 25 eyes of 25 normal subjects were investigated by PS-OCT and corneal and anterior segment (CAS)-OCT. Average of en face phase retardation of the posterior surface of the cornea, curvature, videokeratographic parameters, regular and irregular astigmatism, pachymetry map, and elevation were measured. The AROC of ...

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