1. Spectral-Domain Optical Coherence Tomographic Assessment of Schlemm's Canal in Chinese Subjects with Primary Open-angle Glaucoma

    Spectral-Domain Optical Coherence Tomographic Assessment of Schlemm's Canal in Chinese Subjects with Primary Open-angle Glaucoma

    Purpose To evaluate in vivo features of Schlemm's canal (SC) in patients with primary open-angle glaucoma (POAG) with spectral-domain optical coherence tomography (SD-OCT) and to investigate the relationship of SC size with intraocular pressure (IOP) and glaucoma severity. Design Prospective, comparative study. Participants Fifty Chinese patients with newly diagnosed POAG who had not undergone surgery and 50 normal Chinese subjects from a population-based, cross-sectional study in Shanghai. Methods All participants underwent SD-OCT. The diameter and area of SC were examined in the temporal and nasal sections and measured with customized software. Main Outcome Measures Patient demographics, repeatability and reproducibility ...

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