1. Measuring Retinal Nerve Fiber Layer Birefringence, Retardation, and Thickness Using Wide-Field, High-Speed Polarization Sensitive Spectral Domain OCT

    Measuring Retinal Nerve Fiber Layer Birefringence, Retardation, and Thickness Using Wide-Field, High-Speed Polarization Sensitive Spectral Domain OCT

    Purpose. We presented a novel polarization sensitive optical coherence tomography (PS-OCT) system for measuring retinal nerve fiber layer (RNFL) birefringence, retardation, and thickness, and report on the repeatability of acquiring these quantities. Methods. A new PS-OCT system, measuring at 840 nm, was developed that supports scan angles of up to 40° × 40° with an A-scan rate of 70 kHz. To test the performance and reproducibility, we measured 10 eyes of 5 healthy human volunteers five times each. All volunteers were imaged further with scanning laser polarimetry (SLP). The obtained RNFL birefringence, retardation, and thickness maps were averaged, and standard deviation ...

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